With the upsurge of China' s innovation and entrepreneurship the innovation and entrepreneurship service industry de- velops rapidly． Beijing Shanghai Shenzhen and other areas focus on innovation for en- trepreneurs to provide a full range of services service innovation and entrepreneurship ecological chain． But the innovative service ecological chain still has the unbalanced regional distribution serious homogenization phenomenon ． Through the optimization of relationship of ecological chain nodes between innovation and en- trepreneurship services to improve the development environment innovation and entrepreneurship services eco- logical chain to im- prove the stability and balance of measures of innovation and entrepreneurship services eco- logical chain establish ecological economic integrity circulation and sustainable development of innovation ser- vice chain ．