Challenges and prospects of CAR-T cell therapy in colorectal cancer (CRC)

Yanan Lv

doi:10.47297/wspbdsWSP2752-630501.20250502

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Challenges and prospects of CAR-T cell therapy in colorectal cancer (CRC)

Volume 5, Issue 2

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Challenges and prospects of CAR-T cell therapy in colorectal cancer (CRC)
Challenges and prospects of CAR-T cell therapy in colorectal cancer (CRC)
The Affiliated Middle School of Huazhong University of Science and Technology, Wuhan, Hubei, 430000, China
Vol. 5, Issue 2, Pages: 5-9(2025)
Published：18 June 2025
DOI：10.47297/wspbdsWSP2752-630501.20250502
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Lv Yanan.Challenges and prospects of CAR-T cell therapy in colorectal cancer (CRC)[J].Biomedical Data Science,2025,05(02):5-9.
DOI：

Lv Yanan.Challenges and prospects of CAR-T cell therapy in colorectal cancer (CRC)[J].Biomedical Data Science,2025,05(02):5-9. DOI： 10.47297/wspbdsWSP2752-630501.20250502.

摘要

Abstract

Colorectal cancer (CRC)

also known as "colorectal cancer"

includes colon cancer and rectal cancer

and refers to malignant tumors that occur in the mucosal epithelium and glands of the colon and rectum. The incidence and mortality of CRC are at the forefront of digestive system malignancies. The early symptoms of patients are not obvious. As the disease progresses

there will be changes in bowel habits

changes in stool shape

abdominal pain or abdominal discomfort. Since CRC is harmful to human health

effective treatment methods are needed. From the current research status

Chimeric antigen receptor T cell therapy (CAR-T cell therapy)

as a new type of precise targeted treatment of tumor cells

can play an anti-tumor role in the treatment of CRC. Therefore

this article analyzes the main targets of CAR-T cell therapy for CRC

and then combines the challenges faced by CAR-T cell therapy for CRC to further explore the prospects of CAR-T cell therapy for CRC

aiming to deepen the understanding of CAR-T cell therapy and provide some valuable references for the clinical treatment of CRC patients.

关键词

Keywords

references

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