Research progress of G protein-coupled receptor drugs in nervous system diseases

Youming Zhuo

doi:10.47297/wspbdsWSP2752-630504.20250501

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Research progress of G protein-coupled receptor drugs in nervous system diseases

Volume 5, Issue 1

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Research progress of G protein-coupled receptor drugs in nervous system diseases
Research progress of G protein-coupled receptor drugs in nervous system diseases
Guangdong Medica University, GuangDong, China
Vol. 5, Issue 1, Pages: 19-23(2025)
Published：19 March 2025
DOI：10.47297/wspbdsWSP2752-630504.20250501
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Zhuo Youming.Research progress of G protein-coupled receptor drugs in nervous system diseases[J].Biomedical Data Science,2025,05(01):19-23.
DOI：

Zhuo Youming.Research progress of G protein-coupled receptor drugs in nervous system diseases[J].Biomedical Data Science,2025,05(01):19-23. DOI： 10.47297/wspbdsWSP2752-630504.20250501.

摘要

Abstract

This review explores the research progress of G protein-coupled receptors (GPCRs) in neurological diseases

highlights the central role of GPCRs in the regulation of cognitive function and mood

and discusses their potential therapeutic potential in neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. This review also covers the importance of adhering GPCRs (aGPCRs) in neurodevelopment and discusses the application of structural biology

gene editing

and artificial intelligence in GPCR drug development. Future studies will focus on revealing the detailed mechanism of action of GPCRs to develop more effective therapies.

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Keywords

references

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