Study on the Association Between Gut Microbiota Dysbiosis and the Risk of Alcoholic Hepatitis

Bingxin Wu; Liyan Bai

doi:10.47297/wspbdsWSP2752-630506.20250503

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Study on the Association Between Gut Microbiota Dysbiosis and the Risk of Alcoholic Hepatitis

Volume 5, Issue 3

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Study on the Association Between Gut Microbiota Dysbiosis and the Risk of Alcoholic Hepatitis
Study on the Association Between Gut Microbiota Dysbiosis and the Risk of Alcoholic Hepatitis
School of Life Sciences, Yunnan University, Kunming, Yunnan, 650091, China
Vol. 5, Issue 3, Pages: 31-36(2025)
Published：30 September 2025
DOI：10.47297/wspbdsWSP2752-630506.20250503
Accepted：

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Wu Bingxin,Bai Liyan.Study on the Association Between Gut Microbiota Dysbiosis and the Risk of Alcoholic Hepatitis[J].Biomedical Data Science,2025,05(03):31-36.
DOI：

Wu Bingxin,Bai Liyan.Study on the Association Between Gut Microbiota Dysbiosis and the Risk of Alcoholic Hepatitis[J].Biomedical Data Science,2025,05(03):31-36. DOI： 10.47297/wspbdsWSP2752-630506.20250503.

摘要

Abstract

Based on alcohol-induced gut microbiota imbalance

this study analyzes its relationship with the risk of alcoholic hepatitis. It elucidates the role of microbial homeostasis in maintaining gut-liver axis function

detailing the processes of reduced microbiota diversity

increased barrier permeability

and amplified inflammatory signaling under alcoholic conditions. By examining changes in key bacterial genera and metabolites

the study explores their roles in lipid metabolism disorders and immune activation. Results indicate that dysbiosis promotes alcoholic hepatitis formation through coupled metabolic and inflammatory pathways

revealing its microbiome-mediated pathogenic mechanism.

关键词

Keywords

references

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