New Progress of Nanotechnology in the Diagnosis and Treatment of Oral Cancer

Yi Zhang

doi:10.47297/wspbdsWSP2752-630510.20250501

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New Progress of Nanotechnology in the Diagnosis and Treatment of Oral Cancer

Volume 5, Issue 1

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New Progress of Nanotechnology in the Diagnosis and Treatment of Oral Cancer
New Progress of Nanotechnology in the Diagnosis and Treatment of Oral Cancer
Stomatology major, Northwest University for Nationalities, Gansu, Lanzhou, 730030, China
Vol. 5, Issue 1, Pages: 45-48(2025)
Published：19 March 2025
DOI：10.47297/wspbdsWSP2752-630510.20250501
Accepted：

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Yi Zhang.New Progress of Nanotechnology in the Diagnosis and Treatment of Oral Cancer[J].Biomedical Data Science,2025,05(01):45-48.
DOI：

Yi Zhang.New Progress of Nanotechnology in the Diagnosis and Treatment of Oral Cancer[J].Biomedical Data Science,2025,05(01):45-48. DOI： 10.47297/wspbdsWSP2752-630510.20250501.

摘要

Abstract

Oral cancer is a malignant tumor of the head and neck with rising morbidity and mortality

and traditional treatments often have limitations such as functional damage and side effects. This paper reviews the latest research progress of nanotechnology in the diagnosis and treatment of oral cancer. With its unique physical and chemical properties and ultra-small size effect

nanotechnology shows significant advantages in tumor diagnosis and treatment. In terms of diagnosis

nanotechnology uses highly sensitive biosensors to detect biomarkers

develop new nanomaterials to achieve efficient enrichment of circulating tumor cells

and use nanoprobes to detect cell core acids. In terms of treatment

multi-stage nano-drug delivery systems significantly improve the bioavailability and specificity of drugs through passive and active targeting mechanisms; photodynamic therapy and magneto-thermotherapy based on nanomaterials achieve accurate treatment of tumors. Although nanotechnology has made remarkable progress in the field of diagnosis and treatment of oral cancer

there are still many challenges in large-scale production

safety evaluation and clinical transformation

which need further in-depth research and standardized application.

关键词

Keywords

references

Pei J , Natarajan PM , Umapathy VR , Swamikannu B , Sivaraman NM , Krishnasamy L , Palanisamy CP . Advancements in the Synthesis and Functionalization of Zinc Oxide-Based Nanomaterials for Enhanced Oral Cancer Therapy . Molecules . 2024 , 29 ( 11 ): 2706 .

Guérin M , Lepeltier E . Nanomedicines via the pulmonary route: a promising strategy to reach the target? Drug Deliv Transl Res . 2024 , 14 ( 8 ): 2276 - 2297 .

Cui L , Pi J , Qin B , Cui T , Liu Z , Lei L , Wu S . Advanced application of carbohydrate-based micro/nanoparticles for rheumatoid arthritis . Int J Biol Macromol . 2024 , 269 ( Pt 1 ): 131809 .

Das U , Kapoor DU , Singh S , Prajapati BG . Unveiling the potential of chitosan-coated lipid nanoparticles in drug delivery for management of critical illness: a review . Z Naturforsch C J Biosci . 2024 , 10; 79 ( 5-6 ): 107 - 124 .

Zhang Y. , Li M. , Gao X. , et al . Nanotechnology in cancer diagnosis: progress, challenges and opportunities . Journal of Hematology & Oncology . 2019 , 12 ( 1 ): 137 .

Chen W. H. , Lecaros R. L. , Tseng Y. C. , et al . Nanoparticle delivery of HIF1α siRNA combined with photodynamic therapy as a potential treatment strategy for head-and-neck cancer . Cancer Letters . 2015 , 359 ( 1 ): 65 - 74 .

Jain S. , Hirst D. G. , O'Sullivan J . M . Gold nanoparticles as novel agents for cancer therapy. The British journal of radiology . 2012 , 85 ( 1010 ): 101 - 113 .

Gharat S. A. , Momin M. , Bhavsar C . Oral Squamous Cell Carcinoma: Current Treatment Strategies and Nanotechnology-Based Approaches for Prevention and Therapy . Critical reviews in therapeutic drug carrier systems . 2016 , 33 ( 4 ): 363 - 400 .

Parkhe VS , Tiwari AP . Gold nanoparticles-based biosensors: pioneering solutions for bacterial and viral pathogen detection-a comprehensive review . World J Microbiol Biotechnol . 2024 , 40 ( 9 ): 269 .

Choramle M , Verma D , Kalkal A , Pradhan R , Rai AK , Packirisamy G . L-Cysteine functionalized magnetite nanoparticle adorned Ti3C2-MXene nanohybrid based screen printed immunosensor for oral cancer biomarker detection . Anal Methods . 2024 , 16 ( 29 ): 4938 - 4950 .

Ntadambanya A , Pernier J , David V , Susumu K , Medintz IL , Collot M , Klymchenko A , Hildebrandt N , Le Potier I , Le Clainche C , Cardoso Dos Santos M . Quantum Dot-Based FRET Nanosensors for Talin-Membrane Assembly and Mechanosensing . Angew Chem Int Ed Engl . 2024 , e202409852 .

Chu X , Zhong X , Zang S , Wang M , Li P , Ma Y , Tian X , Yang Y , Wang C , Yang Y . Stem cell-like circulating tumor cells identified by Pep@MNP and their clinical significance in pancreatic cancer metastasis . Front Oncol . 2024 , 14 : 1327280 .

Kefayat A , Sartipzadeh O , Molaabasi F , Amiri M , Gholami R , Mirzadeh M , Shokati F , Khandaei M , Ghahremani F , Poursamar SA , Sarrami-Forooshani R . Microfluidic System Consisting of a Magnetic 3D-Printed Microchannel Filter for Isolation and Enrichment of Circulating Tumor Cells Targeted by Anti-HER2/MOF@Ferrite Core-Shell Nanostructures: A Theranostic CTC Dialysis System . Anal Chem . 2024 , 96 ( 11 ): 4377 - 4384 .

Szymaszek P , Tyszka-Czochara M , Ortyl J . Application of Photoactive Compounds in Cancer Theranostics: Review on Recent Trends from Photoactive Chemistry to Artificial Intelligence . Molecules . 2024 , 29 ( 13 ): 3164 .

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