Preventing and Treating Pediatric Allergic Conjunctivitis via the Gut-Eye Axis from the Spleen

Hong Zeng; Yanlin Zheng

doi:10.47297/wspbdsWSP2752-630517.20260601

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Preventing and Treating Pediatric Allergic Conjunctivitis via the Gut-Eye Axis from the Spleen

Volume 6, Issue 1

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Preventing and Treating Pediatric Allergic Conjunctivitis via the Gut-Eye Axis from the Spleen
Preventing and Treating Pediatric Allergic Conjunctivitis via the Gut-Eye Axis from the Spleen
Eye School of Chengdu University of TCM, Chengdu, Sichuan, 610032, China
Vol. 6, Issue 1, Pages: 78-82(2026)
Published：30 March 2026
DOI：10.47297/wspbdsWSP2752-630517.20260601
Accepted：

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Zeng Hong,Zheng Yanlin.Preventing and Treating Pediatric Allergic Conjunctivitis via the Gut-Eye Axis from the Spleen[J].Biomedical Data Science,2026,06(01):78-82.
DOI：

Zeng Hong,Zheng Yanlin.Preventing and Treating Pediatric Allergic Conjunctivitis via the Gut-Eye Axis from the Spleen[J].Biomedical Data Science,2026,06(01):78-82. DOI： 10.47297/wspbdsWSP2752-630517.20260601.

摘要

Abstract

Allergic Conjunctivitis (AC) is a common immune-related ocular surface disease in children

characterized by a prolonged course and frequent recurrence

which severely impacts patients' quality of life. With its rising global incidence

modern medicine primarily relies on topical anti-allergic treatments that

while controlling symptoms

have limitations in long-term efficacy and recurrence prevention. In contrast

Traditional Chinese Medicine (TCM) offers unique advantages in symptomatic improvement and prevention through holistic management. Based on the emerging "gut-eye axis" theory

this article explores the pathological mechanisms of gut microbiota involvement in AC and the close relationship between the Spleen in TCM and gut microbiota. It proposes that the pathogenesis of pediatric AC stems from "Spleen deficiency as the root

Dampness accumulation as the basis

and Wind-Phlegm attacking the eyes." Emphasizing strengthening the Spleen as the fundamental treatment principle

this paper discusses AC prevention and management from three aspects—"prevention before disease onset

prevention of exacerbation during disease

and prevention of recurrence after disease"—aiming to expand TCM diagnostic and therapeutic approaches for pediatric AC.

关键词

Keywords

references

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