Effect of Radical Resection of Ovarian Cancer Combined with TP Chemotherapy on Coagulation Function and Tumor-related Factors In Patients with Ovarian Cancer

Ying Liu

doi:10.47297/wspbdsWSP2752-630528.20260601

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Effect of Radical Resection of Ovarian Cancer Combined with TP Chemotherapy on Coagulation Function and Tumor-related Factors In Patients with Ovarian Cancer

Volume 6, Issue 1

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Effect of Radical Resection of Ovarian Cancer Combined with TP Chemotherapy on Coagulation Function and Tumor-related Factors In Patients with Ovarian Cancer
Effect of Radical Resection of Ovarian Cancer Combined with TP Chemotherapy on Coagulation Function and Tumor-related Factors In Patients with Ovarian Cancer
Yichang Central People's Hospital (The First College of Clinical Medical Science, China Three Gorges University), Department of Obstetrics and Gynecology, Yichang, Hubei, 443003, China
Vol. 6, Issue 1, Pages: 126-129(2026)
Published：30 March 2026
DOI：10.47297/wspbdsWSP2752-630528.20260601
Accepted：

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Ying Liu.Effect of Radical Resection of Ovarian Cancer Combined with TP Chemotherapy on Coagulation Function and Tumor-related Factors In Patients with Ovarian Cancer[J].Biomedical Data Science,2026,06(01):126-129.
DOI：

Ying Liu.Effect of Radical Resection of Ovarian Cancer Combined with TP Chemotherapy on Coagulation Function and Tumor-related Factors In Patients with Ovarian Cancer[J].Biomedical Data Science,2026,06(01):126-129. DOI： 10.47297/wspbdsWSP2752-630528.20260601.

摘要

Abstract

Objective

To analyze the effect of radical resection of ovarian cancer combined with TP chemotherapy in patients with ovarian cancer.

Methods

Eighty ovarian cancer patients who were admitted to the Department of Gynecology of the First Clinical Medical College of Three Gorges University [Yichang Central People's Hospital] from January 2024 to December 2025 were selected as the research subjects

and all the patients were divided into the control group (n=40

treated with laparotomy radical resection of ovarian cancer) and the research group (n=40

treated based on the control group in combination with TP chemotherapy regimen) according to the random number table

and the coagulation function and tumor-related factors of the two groups were compared using SPSS26.0 statistical software.

Results

(1) Before treatment

P > 0.05; After six cycles of treatment

the coagulation indexes of patients in the two groups were lower than those before treatment

and the index levels in the research group were significantly lower than those in the control group (P < 0.05). (2) Before treatment

P > 0.05; After six cycles of treatment

the levels of NDRG4 in the study group were significantly higher than those in the control group

and the levels of HOXB7 and HK10 were significantly lower than those in the control group (P < 0.05).

Conclusion

The radical resection of ovarian cancer combined with TP chemotherapy can significantly improve the coagulation function and tumor related factors in patients with ovarian cancer.

关键词

Keywords

references

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