Genome Editing Technologies: Development, Mechanisms, and Biomedical Applications

Zhiyi Lin

doi:10.47297/wspbtsWSP2755-952102.20260501

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Genome Editing Technologies: Development, Mechanisms, and Biomedical Applications

Volume 5, Issue 1

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Genome Editing Technologies: Development, Mechanisms, and Biomedical Applications
Genome Editing Technologies: Development, Mechanisms, and Biomedical Applications
International School of Pharmaceutical Business, China Pharmaceutical University, Nanjing, Jiangsu, 211198, China
Vol. 5, Issue 1, Pages: 8-11(2026)
Online First：12 August 2026，

Published：30 March 2026
DOI：10.47297/wspbtsWSP2755-952102.20260501
Accepted：

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Lin Zhiyi.Genome Editing Technologies: Development, Mechanisms, and Biomedical Applications[J].Biomedical Testing & Sensing,2026,05(01):8-11.
DOI：

Lin Zhiyi.Genome Editing Technologies: Development, Mechanisms, and Biomedical Applications[J].Biomedical Testing & Sensing,2026,05(01):8-11. DOI： 10.47297/wspbtsWSP2755-952102.20260501.

摘要

Abstract

Genome editing allows researchers to make precise

targeted changes to the genome of an organism

hailed as one of the most revolutionary biotechnologies of the 21st century. This article provides a detailed overview of the developmental history of genome editing technologies

with a focus on comparing the working principles and technical advantages/disadvantages of ZFNs

TALENs

and CRISPR-Cas systems. It also elaborates on research advancements in areas such as cancer treatment

disease model construction

and genetic disorder therapy. By analyzing the logic and trends of technological iterations

this study aims to offer insights for in-depth research and clinical applications of genome editing technologies.

关键词

Keywords

references

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