Objective: To explore the application methods and effects of autologous bone marrow stem cell transplantation in the clinical treatment of diabetic foot (DF) patients with chronic lower extremity ischemia. Methods: Forty patients with diabetic foot (DF) accompanied by chronic ischemia of lower limbs who were admitted to our hospital for treatment from August 2020 to November 2021 were included in this study. The treatment plan was taken as the basis and they were divided into reference group and experimental group

with 20 cases in each group. The patients were treated with conventional therapy and autologous bone marrow stem cell transplantation therapy

respectively. After the application of differential therapy to the two groups of patients

the nerve conduction velocity of the affected limb of the patients was evaluated

and the effect of this treatment for the patients was compared. Results: The current efficacy of patients in the experimental group was (19/20)95.0%

while that of patients in the reference group was (15/20)75.0%. The nerve conduction velocity of patients in the experimental group was superior to that in the reference group. Conclusion: For patients with diabetic foot (DF) accompanied by chronic ischemia of lower limbs

not only the control of blood glucose should be strengthened

but also autologous bone marrow stem cell transplantation should be adopted for the treatment. With significant efficacy

DF can promote nerve conduction of affected limbs and improve the prognosis of patients

worthy of promotion and application.