The Diagnostic Value of Ultrasound-Guided Fine-Needle Aspiration PTH Testing in Differentiating Thyroid and Parathyroid Lesions

Fan He

doi:10.47297/taposatWSP2633-456906.20250612

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The Diagnostic Value of Ultrasound-Guided Fine-Needle Aspiration PTH Testing in Differentiating Thyroid and Parathyroid Lesions

6卷第12期

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The Diagnostic Value of Ultrasound-Guided Fine-Needle Aspiration PTH Testing in Differentiating Thyroid and Parathyroid Lesions
The Diagnostic Value of Ultrasound-Guided Fine-Needle Aspiration PTH Testing in Differentiating Thyroid and Parathyroid Lesions
Department of Pathology, Yichang Central People's Hospital, Institute of Pathology of China Three Gorges University, Yichang, Hubei, 443002, China
2025年6卷第12期页码：27-29
纸质出版：2025-12-30
DOI：10.47297/taposatWSP2633-456906.20250612
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Fan He. (2025). The Diagnostic Value of Ultrasound-Guided Fine-Needle Aspiration PTH Testing in Differentiating Thyroid and Parathyroid Lesions. 科技理论与实践（英文版）, 6(12), 27-29.

Fan He.The Diagnostic Value of Ultrasound-Guided Fine-Needle Aspiration PTH Testing in Differentiating Thyroid and Parathyroid Lesions[J].Theory and Practice of Science and Technology,2025,06(12):27-29.
Fan He. (2025). The Diagnostic Value of Ultrasound-Guided Fine-Needle Aspiration PTH Testing in Differentiating Thyroid and Parathyroid Lesions. 科技理论与实践（英文版）, 6(12), 27-29. DOI： 10.47297/taposatWSP2633-456906.20250612.

Fan He.The Diagnostic Value of Ultrasound-Guided Fine-Needle Aspiration PTH Testing in Differentiating Thyroid and Parathyroid Lesions[J].Theory and Practice of Science and Technology,2025,06(12):27-29. DOI： 10.47297/taposatWSP2633-456906.20250612.

摘要

Abstract

Accurate diagnosis of endocrine gland lesions in the neck is essential for formulating appropriate surgical plans. However

thyroid nodules and parathyroid adenomas exhibit significant overlap in imaging features

making morphological diagnosis alone prone to misdiagnosis. This study examines the clinical value and pathophysiological basis of ultrasound-guided fine-needle aspiration of parathyroid hormone (FNA-PTH) in distinguishing the tissue origin of suspicious neck nodules. By analyzing the functional characteristics of parathyroid lesions

we elucidate how FNA-PTH testing overcomes the limitations of traditional cytological morphology

shifting from anatomical localization to functional characterization. The paper examines the standardized operating procedures for this technique

the determination of diagnostic thresholds

and the enhanced performance when combined with cytology. It also analyzes its application in complex clinical scenarios such as ectopic parathyroid glands within the thyroid and postoperative recurrence of hyperparathyroidism.

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references

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Youngwirth, L., Benavidez, J., Sippel, R., & Chen, H. (2010). Parathyroid hormone deficiency after total thyroidectomy: incidence and time. Journal of Surgical Research, 163(1), 69-71.

Mosekilde, L., & Christensen, M. S. (1977). Decreased parathyroid function in hyperthyroidism: interrelationships between serum parathyroid hormone, calcium-phosphorus metabolism and thyroid function. European Journal of Endocrinology, 84(3), 566-575.

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