3卷 第6期
The Affiliated Calmette Hospital of Kunming Medical University
纸质出版日期： 2022-06-25 ，
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(2022). Association between KIR Gene Polymorphism and Diabetes After Liver Transplantation. 科技理论与实践（英文版）, 3(6), 66-69.
Liu Fang,Han Lei,Zhang Xibing.Association between KIR Gene Polymorphism and Diabetes After Liver Transplantation[J].Theory and Practice of Science and Technology,2022,03(06):66-69.
(2022). Association between KIR Gene Polymorphism and Diabetes After Liver Transplantation. 科技理论与实践（英文版）, 3(6), 66-69. DOI： 10.47297/taposatWSP2633-456910.20220306.
Liu Fang,Han Lei,Zhang Xibing.Association between KIR Gene Polymorphism and Diabetes After Liver Transplantation[J].Theory and Practice of Science and Technology,2022,03(06):66-69. DOI： 10.47297/taposatWSP2633-456910.20220306.
One of the most frequent problems following liver transplantation is post-transplantation diabetes mellitus (PTDM)
which has a significant negative impact on the medium- and long-term quality of life of liver transplant recipients. A significant risk factor for the incidence and progression of PTDM is genetics. Killer cell immunoglobulin-like receptors (KIR) are expressed on the surface of NK cells and T cells and are members of the immunoglobulin superfamily. By identifying the appropriate ligand molecules on the surface of target cells
KIR controls the activity of NK cells and T cells. It influences Type 2 Diabetes Mellitus' (T2DM) onset and development. KIR gene polymorphism is related with T2DM
and the etiology of PTDM is comparable to that of T2DM. As a result
it may offer novel approaches to the prevention and management of diabetes following liver transplantation.
Gene polymorphismKIR genotype
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