Study on the Damage Effects of Ionizing Radiation on Thymus and Spleen Immune Organs in Mice

Zhi Cheng; Xiwen Sun; Yachong Hu; Mengjuan Shang; Qiling Liu

doi:10.47297/wspbdsWSP2752-630543.20260601

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Study on the Damage Effects of Ionizing Radiation on Thymus and Spleen Immune Organs in Mice

6卷第1期

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Study on the Damage Effects of Ionizing Radiation on Thymus and Spleen Immune Organs in Mice
Study on the Damage Effects of Ionizing Radiation on Thymus and Spleen Immune Organs in Mice
1.School of Public Health, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, China
2.Department of Radiation Protection Medicine, Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, Faculty of Preventive Medicine, The Fourth Military Medical University, Xi'an, Shaanxi, 710032, China
2026年6卷第1期页码：195-198
纸质出版：2026-03-30
DOI：10.47297/wspbdsWSP2752-630543.20260601
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Zhi Cheng, Xiwen Sun, Yachong Hu, Mengjuan Shang & Qiling Liu. (2026). Study on the Damage Effects of Ionizing Radiation on Thymus and Spleen Immune Organs in Mice. 生物医学大数据, 6(1), 195-198.

Cheng Zhi,Sun Xiwen,Hu Yachong,et al.Study on the Damage Effects of Ionizing Radiation on Thymus and Spleen Immune Organs in Mice[J].Biomedical Data Science,2026,06(01):195-198.
Zhi Cheng, Xiwen Sun, Yachong Hu, Mengjuan Shang & Qiling Liu. (2026). Study on the Damage Effects of Ionizing Radiation on Thymus and Spleen Immune Organs in Mice. 生物医学大数据, 6(1), 195-198. DOI： 10.47297/wspbdsWSP2752-630543.20260601.

Cheng Zhi,Sun Xiwen,Hu Yachong,et al.Study on the Damage Effects of Ionizing Radiation on Thymus and Spleen Immune Organs in Mice[J].Biomedical Data Science,2026,06(01):195-198. DOI： 10.47297/wspbdsWSP2752-630543.20260601.

摘要

Abstract

Ionizing radiation

widely used in medical diagnostics

nuclear industry

and scientific research

has potential immunotoxic effects on organisms. The thymus and spleen

as primary immune organs

play a central role in maintaining immune homeostasis. This study systematically evaluated the effects of different doses of ionizing radiation on the structure and function of the thymus and spleen in mice

combining assessments of immune cell counts

histological changes

and immune factor levels. The results showed that ionizing radiation significantly induced thymic atrophy

spleen structural disorder

and lymphocyte reduction

with the degree of damage positively correlated with radiation dose. These findings provide a scientific basis for understanding radiation-induced immune injury mechanisms

developing protective strategies

and guiding clinical interventions.

关键词

Keywords

references

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