Some Methods about Protein Cyclisation

Lezhi Wang

doi:10.47297/taposatWSP2633-456903.20230402

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Volume 4, Issue 2

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Some Methods about Protein Cyclisation
Some Methods about Protein Cyclisation
West China School of Pharmacy, Sichuan University, Chendu Sichuan,P.R. China,610065
Vol. 4, Issue 2, Pages: 18-23(2023)
Published： 2023 ，
DOI：10.47297/taposatWSP2633-456903.20230402
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LEZHI WANG. (2023). Some Methods about Protein Cyclisation. Theory and Practice of Science and Technology, 4(2), 18-23..
DOI：

LEZHI WANG. (2023). Some Methods about Protein Cyclisation. Theory and Practice of Science and Technology, 4(2), 18-23.. DOI： 10.47297/taposatWSP2633-456903.20230402.

摘要

Abstract

Proteins are crucial to exerting biological functions

while they are stable under some specific circumstances limiting their widely use in various fields. One approach called protein cyclisation

especially cyclised polypeptides which are proved to be beneficial to the stability of proteins both in laboratory and nature world

they are expected to have a widely use in many fields including food

health care and pharmaceutical industries. So it is of great importance to develop approaches to achieve the cyclisation of protein and peptides

fortunately

a lot of related researches have been reported over the past few decades. This review illustrates some approaches about protein cyclisation

including chemical methods and enzymatic methods

and some features of each approach and under what conditions it would be the best choice are discussed

advantages and limitations are also discussed in this article.

关键词

Keywords

Protein cyclisationChemical methodsEnzymatic methodsAdvantages and limitations

references

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